What biologics are available?
There are many biologics that can be used to treat IBD. It can be hard to figure out which one is right for you.
While all biologics work well in treating IBD, they also have important differences: their mechanism of action is different, and some biologics may have non-IBD indications.
| Way biologic works | Name | Used in non-IBD conditions |
|---|---|---|
| Blocks tumor necrosis factor (anti-TNF) | Cimzia® (certolizumab pegol) Humira® (adalimumab) Remicade® (infliximab) Simponi® (golimumab) | Yes* |
| Blocks interleukins (anti-IL) | Stelara® (ustekinumab) | Yes* |
| Blocks integrins (anti-integrin) | Entyvio® (vedolizumab) | No (gut-selective) |
| * These medicines may also be used in psoriatic arthritis, plaque psoriasis, rheumatoid arthritis, ankylosing spondylitis, and juvenile idiopathic arthritis. | ||